產(chǎn)品詳情
簡單介紹：
Anti-Cleaved Caspase 3 (Asp175) Rabbit mAb
Size: 100 ul
Concentration: 1 mg/ml
詳情介紹：
Anti-Cleaved Caspase 3 (Asp175) Rabbit mAb
Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase 3 has been extensively studied and implicated to play an important role in apoptosis. Active caspase 3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP). This affinity purified antibody recognizing the active forms of caspase-3 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.
- Overview
-
- Description
- anti- Cleaved Caspase 3 (Asp175) rabbit monoclonal antibody
- Reactivity
-
Human
- Tested applications
- WB: 1/1000, IHC: 1/50-1/200, ICC/IF: 1/50-1/200
- Properties
-
- Immunogen
- Synthetic peptide mapping to the N-terminus adjacent to human active Caspase-3 (p17 subunit)
- Clonality
- Monoclonal, clone number: 4N10
- Isotype
- IgG
- Form
-
Liquid
Preservative: 0.02% Sodium Azide
and 50% glycerol.
- Storage instruction
- Store at -20°C, Avoid freeze / thaw cycle. Do not aliquot the antibody.
- Database links
- Swiss Prot：P42574
- Applications
-
- WB Image
-
Western blot - Cleaved Caspase 3 antibody (EB-AT0551) at 1/1000 dilutionSample: in Jurkat cell lysate treated with Camptothecin.Observed band size: 17kDa
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