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產(chǎn)品詳情

  • 產(chǎn)品名稱：CD48 protein (STJP000142)

  • 產(chǎn)品型號(hào)：STJP000142-50
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
CD48 protein (STJP000142)
詳情介紹：
Host: CHO cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: CD48-protein was developed from cho cells. For use in research applications.
Formulation: PBS pH 7.4
Purification: Purified by ion-exchange chromatography, hydrophobic interaction chromatography and gel-filtration from serum-free CHO growth media
Concentration: 1 mg/ml
Storage Instruction: Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
Gene Symbol: Cd48
Gene ID: 12506
Uniprot ID: CD48_MOUSE
Immunogen: Protein contains mouse CD48 chain (aa 23-217) , propeptide (aa 218-240) is removed
Function Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name Cd48 Antigen
Bcm1 Surface Antigen
Blast-1
Hm48-1
Mrc Ox-45 Surface Antigen
Slam Family Member 2
Slamf2
Signaling Lymphocytic Activation Molecule 2
Sgp-60
Cd Antigen Cd48
Database Links Reactome: R-MMU-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Protein Names Cd48 Antigen protein
Bcm1 Surface Antigen protein
Blast-1 protein
Hm48-1 protein
Mrc Ox-45 Surface Antigen protein
Slam Family Member 2 protein
Slamf2 protein
Signaling Lymphocytic Activation Molecule 2 protein
Sgp-60 protein
Cd Antigen Cd48 protein
Cd48 protein
Bcm-1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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