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簡單介紹：

Cardiac Troponin complex protein (STJP000154)

詳情介紹：

Host:	CHO cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Cardiac Troponin complex-protein was developed from cho cells. For use in research applications.

Formulation:	25 mM Tris, pH 7.5, 500 mM NaCl5 mM CaCl2, 15 mM Beta-mercaptoethanol
Purification:	Antibody-affinity purification following desalting
Concentration:	1 mg/ml
Storage Instruction:	Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles

Post Translational Modifications	Phosphorylated at Ser-42 and Ser-44 by PRKCE.phosphorylation increases myocardium contractile dysfunction. Phosphorylated at Ser-23 and Ser-24 by PRKD1.phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T).
Function	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Protein Name	Troponin I - Cardiac Muscle Cardiac Troponin I
Database Links	Reactome: R-HSA-390522 Reactome: R-HSA-5578775
Alternative Protein Names	Troponin I - Cardiac Muscle protein Cardiac Troponin I protein TNNI3 protein TNNC1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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