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產(chǎn)品名稱：ADCY7 Positive Control for STJ502074 peptide (STJ504558)
產(chǎn)品型號：STJ504558-5
產(chǎn)品廠商：ST john's laboratory
產(chǎn)品文檔：

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簡單介紹：

ADCY7 Positive Control for STJ502074 peptide (STJ504558)

詳情介紹：

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	ADCY7 Positive Control for STJ502074 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range:	WB: 1:500
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Adcy7
Gene ID:	11513
Uniprot ID:	ADCY7_MOUSE
Specificity:	This is positive control is recommended for use in combination with ADCY7 antibody STJ502074.

Tissue Specificity	Most abundant in heart, spleen and lung.
Post Translational Modifications	Phosphorylated by PRKCD.
Function	Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G alpha protein with GNA13. Also, during inflammation, mediates zymosan-induced increase intracellular cAMP, leading to protein kinase A pathway activation in order to modulate innate immune responses through heterotrimeric G proteins G(12/13). Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G protein with G beta:gamma complex. Functions, through cAMP response regulation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regulate LPS-induced TNF-alpha production. However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regulating cAMP synthesis in both B and T cells.
Peptide Name	Adenylate Cyclase Type 7 Atp Pyrophosphate-Lyase 7 Adenylate Cyclase Type Vii Adenylyl Cyclase 7
Database Links	Reactome: R-MMU-163615 Reactome: -MMU-170660 Reactome: -MMU-170670 Reactome: -MMU-418597 Reactome: -MMU-5610787
Cellular Localisation	Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	Adenylate Cyclase Type 7 protein Atp Pyrophosphate-Lyase 7 protein Adenylate Cyclase Type Vii protein Adenylyl Cyclase 7 protein Adcy7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產(chǎn)品名稱：ADCY7 Positive Control for STJ502074 peptide (STJ504558)